Sexualy Transmited Diseases: Hemophilia Essay -- Genetic Bleeding Dis

Hemophilia is a genetic bleeding disorder that slows prevail over the clotting process of ones blood. on that point are cardinal types of the disorder hemophilia A and hemophilia B. Both result in very similar symptoms, however, they are caused by different versions of genes on the X chromosome. The way in which the disorder is inherited is known as an X-linked recessive pattern. Since males only have one X chromosome, one gene mutation is all that is needed in order to obtain hemophilia. On the opposite hand, females have two X chromosomes meaning that two mutations (on on each X chromosome) are required to inherit hemophilia. For that reason, its far much unlikely for females to have hemophilia than it is for males. Specifically, the genes which cause hemophilia A and hemophilia B are the F8 gene and the F9 gene respectively. Mutations in these genes trigger the outturn of abnormal versions or reduce the number of coagulation brokers VIII or IX. Subsequently, these missi ng or scarce proteins are not able to assistance in the blood clotting process which causes excessive and continuous bleeding. There are varying levels of the severity of hemophilia which are all dependent on the extent of mutation of coagulation factors VIII or IX (Hemophilia, n.d.).There is, however, another form of hemophilia that is rare. It is known as acquired hemophilia, and it is caused by ones body producing specialized proteins (autoantibodies) that attack coagulation factor VIII. In this rare case, it is not caused by genetic mutation or scarcity. The bodys production of autoantibodies can sometimes be attributed to pregnancy, hypersensitised reactions, cancer, or immune system disorders (Hemophilia, n.d.).SymptomsSomeone that is affected by hemophilia would be prone to ... ... 19, 2014, from https//online.epocrates.com/u/2923468/Hemophilia/Basics/EpidemiologyHemophilia. (n.d.). Retrieved inch 16, 2014, from http//ghr.nlm.nih.gov/ direct/hemophiliaHemophilia. (n.d.). Retrieved March 16, 2014, from http//www.mayoclinic.org/diseases-conditions/hemophilia/basics/symptoms/con-20029824How Is Hemophilia Treated? (n.d.). Retrieved March 17, 2014, from https//www.nhlbi.nih.gov/health/health-topics/topics/hemophilia/treatment.htmlInheritance Pattern of Hemophilia. (n.d.). In Hemophilia federation of America. Retrieved March 20, 2014, from http//www.hemophiliafed.org/bleeding-disorders/hemophilia/inheritance/The N-terminal Epidermal Growth Factor-like Domain in Factor IX and Factor X Represents an Important Recognition theme for Binding to Tissue Factor*. (n.d.). Retrieved March 18, 2014, from http//www.jbc.org/content/277/5/3622